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Andrés Holguín desde el año 2006 es Coordinador de Investigaciones Tecnológicas e Innovación y Seguridad de la Información en la Dirección de Servicios de Información y Tecnología (DSIT) de la Universidad de los Andes (en la que trabaja desde el año 2002). Desde esta posición se encarga de la seguridad de la información; adicionalmente tiene a su cargo los servicios de cómputo avanzado para investigación y los de innovación.
Holguín es Ingeniero de Sistemas y Computación de la Universidad de los Andes y cuenta con certificaciones en Seguridad de la Información de ISCA CISM y SANS GCED.