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Andrés Holguín é, desde 2006, o coordenador de Pesquisas Tecnológicas, Inovação e Segurança da Informação na Direção de Serviços de Informação e Tecnologia (DSIT) da Universidade dos Andes, na qual trabalha desde 2002. Neste cargo, é o responsável pela Segurança da Informação. Também é responsável pelos serviços de computação avançada para pesquisa e de inovação.
Holguín é Engenheiro de Sistemas e Computação da Universidade dos Andes e conta com certificações em Segurança da Informação de ISCA CISM y SANS GCED.